The planned poster presentations include:
- Change from Baseline in Clinical Dementia Rating Scale Cognitive
and Functional Domains in PRIME, a Randomized Phase 1b Study of the
Anti-Amyloid Beta Monoclonal Antibody Aducanumab (BIIB037). Poster
1-053: July 16, 2017, 9:30 a.m. GMT+1. This new post-hoc analysis
shows the change in the cognitive and functional subscores, which are
derived from the previously reported clinical dementia rating (CDR)
score for the overall and early Alzheimer’s disease populations in the
1, 3, 6 and 10 mg/kg aducanumab fixed-dosing cohorts in Phase 1b.
This poster will be available concurrently with the session on the Investors section of the Biogen company website, www.Biogen.com.
- Signs and Symptoms of Alzheimer’s Disease Noted in Health Records up to 5 Years Prior to Diagnosis. Poster 2-275: July 17, 2017, 9:30 a.m. GMT+1. This analysis reports the documentation of cognitive and behavioral impairment from U.S. medical health records, prior to an Alzheimer’s disease diagnosis.
Aducanumab (BIIB037) is an investigational compound being developed for the treatment of early Alzheimer’s disease. Aducanumab is a human recombinant monoclonal antibody (mAb) derived from a de-identified library of B cells collected from healthy elderly subjects with no signs of cognitive impairment or cognitively impaired elderly subjects with unusually slow cognitive decline using Neurimmune’s technology platform called Reverse Translational Medicine (RTM). Biogen licensed aducanumab from Neurimmune under a collaborative development and license agreement.
Through cutting-edge science and medicine, Biogen discovers, develops and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Founded in 1978, Biogen is a pioneer in biotechnology, and today the company has the leading portfolio of medicines to treat multiple sclerosis; has introduced the first and only approved treatment for spinal muscular atrophy; and is at the forefront of neurology research for conditions including Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis. Biogen also manufactures and commercializes biosimilars of advanced biologics. For more information, please visit www.biogen.com. Follow us on social media – Twitter, LinkedIn, Facebook and YouTube.
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